7 Positive Signs After Embryo Transfer 7 Positive Signs After Embryo Transfer

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14 minute read Updated on 10th November 2025

7 Positive Signs After Embryo Transfer

Written by David Letsa, MD
Medically reviewed by Katerina Shkodzik, MD, Ob&Gyn

An embryo transfer is a crucial step in In Vitro Fertilization (IVF). This procedure involves the careful placement of one or more embryos, created by fertilizing an egg with sperm in a nurturing laboratory environment, into a woman's uterus. The ultimate hope is that the embryo finds a cozy spot in the uterine lining and begins establishing a pregnancy.

While the procedure is usually quick and gentle, not unlike a routine Pap smear, it carries profound emotional weight and hope for those involved, making it a truly special moment in the IVF journey.

IVF is an effective option for those facing fertility challenges or building a family through alternative means. The two-week wait after an embryo transfer is filled with anticipation and hope, where every new feeling may seem like a sign of success. For many undergoing IVF, positive signs after embryo transfer can feel like an emotional lifeline. After weeks or months of injections, appointments, and procedures, the physical and emotional toll is immense.

The presence of early symptoms such as mild cramping, light spotting, or fatigue can offer a sense of hope and reassurance that the body is responding positively and that the process may have been successful. However, understanding the reasons behind these signs can be helpful, along with practical advice for managing this emotionally charged period.

Positive Signs After Embryo Transfer

Navigating early pregnancy signs can be a profound mix of emotions, filled with both excitement and anxiety, regardless of whether conception occurred naturally or through IVF. While the ultimate hope is for a healthy pregnancy, the paths we take can vary significantly. It's only natural to wonder if the symptoms following an IVF embryo transfer reflect those of a natural conception. 

Gaining insight into the similarities and differences can provide comfort and reassurance during this transitional period. Let's take a look at the signs and experiences from conception through the first trimester.

Comparison of Natural and IVF Pregnancy Symptoms

Symptom

IVF Pregnancy

Natural Pregnancy

Bloating

Often more pronounced due to fertility medications and fluid retention

It can occur, but it is generally milder at the very start of pregnancy

Breast Tenderness

Very common due to progesterone supplements. It can be a confusing symptom.

A classic early sign due to the natural surge in progesterone and estrogen

Cramping & Spotting

It can be caused by implantation or medication side effects. Often a source of anxiety.

Often seen as a sign of implantation, which is a key hopeful sign

Nausea

It can be caused by rising hCG levels or medication side effects

A classic sign of rising hCG is often referred to as "morning sickness"

Fatigue

Extremely common due to high progesterone levels and stress of the IVF process

A very common early sign is that the body's energy is redirected to pregnancy


After an embryo transfer, your body begins a complex and delicate process aimed at achieving a successful pregnancy. The symptoms you might experience are often the result of this process, particularly the production of hormones that support a new life. These early symptoms after embryo transfer can be a source of reassurance, but it's crucial to understand that their absence does not signify failure.

Here is a short key takeaway list of some of the most hopeful signs:

  • Light spotting or implantation bleeding

  • Mild cramping or pelvic discomfort

  • Breast tenderness or enlargement

  • Fatigue and increased sleepiness

  • Hormonal influences on early pregnancy signs

It's understandable to feel confused during this time, as your body undergoes various hormonal changes. Suppose you're going through an IVF cycle. In that case, the progesterone and estrogen supplements can produce sensations that mimic early pregnancy symptoms, which can make it hard to discern what you might be truly experiencing.

Progesterone plays a crucial role in preparing your uterine lining for implantation, and it’s completely normal to notice common signs like breast tenderness, bloating, or fatigue. Please know that feeling uncertain is a natural part of this journey. It’s important to remind yourself that these symptoms are just possibilities and not certainties. A blood test will provide you with the clarity and reassurance you need.

The Hormone Health Clinic for Fertility recognizes how challenging the journey to conception can be. They offer compassionate support tailored to individual needs, helping monitor hormonal changes and create a customized plan to enhance the chances of conception after IVF. This guidance can provide a sense of control during an often overwhelming time.

Fertility medications can influence symptom severity and timing, causing sensations similar to early pregnancy signs. Ovarian stimulation and progesterone supplements prepare the body for pregnancy, but their side effects can be confusing. Symptoms vary greatly among individuals; some may notice changes soon after the transfer, while others may not feel anything until much later or at all. Understanding this variation can help reduce anxiety during the process.

7 Symptoms and Body Changes After Embryo Transfer

Understanding the changes in your body can help you approach this journey with compassion. When implantation occurs, the embryo gently settles into the uterine wall, which may cause some minor sensations or spotting. Remember, the changes you feel are normal, and it's essential to take care of yourself during this transformative time. 

Bloating After Embryo Transfer

Feeling swollen or bloated is one of the most common physical signs of implantation after embryo transfer. Progesterone can slow digestion by relaxing the smooth muscles in the digestive tract, leading to gas and bloating. Hormonal changes, especially increases in estrogen and progesterone, may also cause water retention, resulting in a puffy feeling. To manage discomfort, stay hydrated, eat small, frequent meals, and include fiber-rich foods, while avoiding carbonated drinks and salty foods that can worsen fluid retention.

Nausea After Embryo Transfer

Nausea often occurs in the later stages of the first trimester but can start early in pregnancy due to a sharp rise in hCG levels. Some individuals may also feel queasy during the two-week wait, which can indicate pregnancy. It can be hard to differentiate between hormonal side effects and actual pregnancy-related nausea, so persistent or worsening nausea may signal pregnancy. Starting prenatal vitamins early can improve nutrient intake and may help reduce nausea linked to deficiencies.

Tight Stomach After Embryo Transfer

Many experience tightness or mild pressure in the belly due to uterine expansion and increased blood flow as the uterus adapts to pregnancy. Ovarian enlargement from stimulation medications can also contribute to this sensation. While mild discomfort is normal, severe or persistent pain should be discussed with a doctor. 

Light Spotting or Implantation Bleeding

Light spotting, typically pink or brown, that occurs a few days after the transfer is often linked to the embryo attaching to the uterine lining. This type of spotting is called implantation bleeding. It is usually much lighter and shorter than a menstrual period. It is often one of the most confusing embryo transfer symptoms. If you are concerned, consult your healthcare provider.

Mild Cramping or Pelvic Discomfort

A mild cramping sensation can feel similar to premenstrual cramps but is generally less intense and may be related to implantation or the use of progesterone therapy.

Breast Tenderness or Swelling

Hormonal changes directly affect your breast tissue, leading to increased sensitivity, fullness, or tingling caused by rising progesterone and estrogen, which are preparing the body for lactation.

Increased Urination

If you find yourself making more frequent trips to the bathroom, it could be a sign. An early rise in hCG and progesterone can increase blood flow to the pelvic area and impact kidney function, leading to increased urination.

Changes in Vaginal Discharge

Thin, white, and mild-smelling discharge is common. This type of discharge is a normal result of the hormonal shifts and increased blood flow to the area.

Fatigue and Low Energy

Your body is working overtime to build a new home, and the higher progesterone levels can make you feel exhausted and ready for a nap at any time.

No Symptoms After Embryo Transfer — Is That Normal?

This is a question that weighs heavily on many people's minds during the two-week wait. The answer, definitively, is yes. The absence of symptoms is entirely normal. Many successful IVF pregnancies occur with no noticeable symptoms in the first few weeks. The body's response to hormonal changes and implantation varies significantly from person to person. 

About 15% patients who feel "nothing" special go on to have a positive pregnancy test. Every person's sensitivity to hormonal fluctuations is different. What causes a noticeable symptom in one person may not be felt by another, even with the same hormone levels.

The best approach is to manage your expectations and focus on self-care. Remind yourself that after IVF, symptoms of pregnancy do not always predict the outcome. Engage in activities that bring you joy and help you relax to reduce anxiety.

The Mira Hormone Monitor, Wands, Mira App, and the BBT can provide reassurance by allowing you to track hormone trends even without physical symptoms. The data can give you a more objective view of what is happening inside your body, helping alleviate some of the anxiety associated with a symptom-free wait.

Disclaimer: The Mira Hormone Monitor, Wands, Mira App, and BBT tracking tools are intended for fertility awareness and cycle tracking purposes only. These products are not intended to diagnose, treat, cure, prevent any disease, to diagnose or track pregnancy, or serve as a form of contraception. The information provided through these tools should not substitute for professional medical advice, diagnosis, or treatment. Individual results and cycle patterns may vary. Users should always consult with qualified healthcare providers regarding fertility, conception, and reproductive health matters.

Negative Signs After Embryo Transfer

While most symptoms are either neutral or positive, there are a few red flags you should watch for.

  • Severe pain, heavy bleeding, fever, or painful urination 

  • Severe pain can indicate ovarian torsion (a twisting of the ovary) or a pelvic infection 

  • Heavy, bright red bleeding can be a sign that a period is beginning

Always contact your clinic immediately if you experience any of these symptoms.

Day-by-Day Timeline of Symptoms After Embryo Transfer

Day After Embryo Transfer

Possible Symptoms / Body Changes

Day 1

Usually, there are no noticeable symptoms, except for mild cramping or pelvic discomfort from the procedure itself, and light fatigue from medications

Day 2

Mild cramping, slight bloating, emotional changes; often caused by progesterone rather than implantation

Day 3

Light spotting may occur (early implantation in rare cases), breast tenderness, or no symptoms at all

Day 4

Fatigue, mood swings, and continued bloating; still too early for definitive pregnancy signs

Day 5

Possible start of breast tenderness, mild nausea, increased urination, constipation, and hormonal side effects are common

Day 6

Light implantation bleeding for some; cramping, bloating, sore nipples, or no changes

Day 7

Pink or brown spotting, headaches, mild nausea, breast tenderness; signs may still be subtle

Day 8

Similar to day 7, a slight increase in fatigue or hunger, and emotional sensitivity

Day 9

IVF success symptoms may become more noticeable: increased thirst, breast changes; some may get a very faint positive on a sensitive pregnancy test

Day 10

Mild uterine stretching sensations, mood swings, fatigue; pregnancy hormone (hCG) may be detectable in some cases

Day 11

Symptoms of successful embryo transfer, like morning sickness, breast enlargement, bloating, fatigue, and frequent urination, may be more pronounced. Light cramping as the uterus adapts.

Day 12

Stronger early pregnancy symptoms for some: fatigue, morning nausea, tender breasts; light spotting possible

Day 13

Noticeable changes in appetite, heightened sense of smell, bloating; some may experience dizziness

Day 14-20

End of two-week wait time for pregnancy test; symptoms may include missed period, stronger fatigue, breast swelling, or still no symptoms at all

Day 21

Morning sickness, mood changes, dizziness, breast tenderness, and increased urination; the embryo is firmly implanted


When to Do a Pregnancy Test After Blastocyst Transfer

The excitement of waiting for results can be immense, but patience is key. When it comes to pregnancy tests after embryo transfer and IVF, not all tests are created equal. The clinic will give you a specific date for your blood test, known as the beta hCG test.

  • Why clinics recommend waiting 10–14 days: This waiting period allows enough time for hCG levels to rise to a detectable level. A test taken too early could result in a false negative.

  • How hCG levels develop after implantation: Once the embryo has successfully implanted, it begins to produce the hCG hormone. The levels double approximately every 48-72 hours.

  • Risks of false positives and false negatives: Taking an at-home pregnancy test after embryo transfer too early can lead to a false negative if hCG levels are not yet high enough. A false positive can also occur if you have received an hCG trigger shot, as the residual hormone may still be in your system.

Takeaway: Managing the Two-Week Wait

The two-week wait can be emotionally challenging, so it's essential to prioritize your wellbeing. Focus on rest, nourishing your body, and seeking support. Be gentle with yourself, allow for rest, choose wholesome foods, and stay hydrated. Consider minimizing strenuous activities and avoiding alcohol and tobacco to support a healthy pregnancy.

Prepare your heart and mind for any outcome. While hoping for a positive result is natural, being ready for either possibility can foster resilience. Remember to care for yourself; you deserve compassion during this delicate time.

Frequently Asked Questions 

No symptoms after embryo transfer, is that normal?

Yes, it is entirely normal and does not indicate any failure on your part. Many successful pregnancies occur without any noticeable symptoms during the two-week wait.

What do I do after an embryo transfer?

Focus on self-care: stay hydrated, eat healthy foods, get plenty of rest and avoid strenuous activity, alcohol and tobacco.

Why am I spotting 10 days after an embryo transfer?

This is often a sign of implantation bleeding, which is light, pink, or brown spotting that can occur as the embryo burrows into the uterine lining.

What is the first sign of pregnancy after an IVF embryo transfer?

For many, the first sign is often a feeling of mild cramping or light spotting, which is related to implantation.

Do's and Don'ts after an embryo transfer in IVF?

Do's: Rest, eat a balanced diet, stay hydrated, and practice gentle movement. 

Don'ts: Avoid strenuous exercise, alcohol, hot tubs and heavy lifting.

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